Prevalence of BRCA homopolymeric indels in an ION Torrent-based tumour-to-germline testing workflow in high-grade ovarian carcinoma

Abstract Tumour DNA sequencing is essential for precision medicine since it guides therapeutic decisions but also fosters the identification of patients who may benefit from germline testing.Notwithstanding, the bullard usrx tumour-to-germline testing workflow presents a few caveats.The low sensitivity for indels at loci with sequences of identical

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Zymobacter palmae Pyruvate Decarboxylase is Less Effective Than That of Zymomonas mobilis for Ethanol Production in Metabolically Engineered Synechocystis sp. PCC6803

To produce bioethanol from model cyanobacteria such as Synechocystis, a two gene cassette consisting of genes encoding pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) are required quadruple ointment for dogs to transform pyruvate first to acetaldehyde and then to ethanol.However the partition of pyruvate to ethanol comes at a cost, a r

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